WP4. Phage-based biopurification
Lead partner: KUL/QIB
Participation: UW, TUD
Identification, characterization, selection of phages and production of phages cocktails targeting wastewater-borne ARB, especially ESKAPE pathogens.
4.1. Creation of extended ESKAPE phage collection.
4.2. Characterization of phages for bioremediation.
4.3. Development of qPCR assays for phage monitoring.
4.4. Development of application-ready phage cocktail.
M5. Development of phage cocktails targeting ESKAPE pathogens and optimized for ARB bioremediation.
D10. Extended collection of ~50 phages covering the ESKAPE pathogens and high quality phage genome annotations.
D11. Development of the PhageLand BioBank (15-20 phages).
D12. Design of qPCR primers and probes for BioBank phages testing.
D13. Standard Operation Procedures (SOP) for the application of phage cocktails.
D14. Application-ready phage cocktail and assessment on the effectiveness of phage cocktails for the removal of target ARBs.