Duration: 3 years
Start date: Feb. 1st 2022
End date: Jan. 31st 2025
JPIAMR-ACTION
Join Transnational Call for Proposals 2021
“One Health interventions to prevent or reduce the development and transmission of antimicrobial resistance”.
/SUMMARY
PhageLand aims to develop a novel intervention stategy
Combining the low-cost and eco-friendly purification capacity of passive treatment systems, namely constructed wetlands (CW), with a dedicated phage-based treatment to prevent the transmission of antibiotic resistance (AR) from wastewater into surface waters.
PhageLand includes public health investigations targeting multidrug-resistant bacterial (ARB) pathogens in low-middle income countries (LMICs) in Eastern Europe. The phage-based treatment will be specifically tailored to eliminate these multidrug-resistant pathogens from wastewater. In parallel, PhageLand aims to assess: a) the self-purification capacity of model full-scale CWs operating in Spain and Moldova in removing antibiotic residues, ARB and antibiotic resistance genes (ARGs); and b) the potential risk associated with the dissemination of ARB and ARGs within indigenous bacterial communities and among animals inhabiting CWs.